
About Mithrl
Automating bioinformatics for faster scientific discovery
Key Highlights
- Headquartered in San Francisco, California
- Specializes in automating NGS data workflows
- Utilizes AI and natural language processing
- Team size of 11-50 employees
Mithrl is an AI-powered platform headquartered in San Francisco, California, that automates Next-Generation Sequencing (NGS) data workflows for scientific labs. With its innovative use of natural language processing, Mithrl generates custom bioinformatics pipelines in minutes, significantly reducing...
π Benefits
Mithrl offers competitive salaries, equity options, flexible PTO, and a remote-friendly work policy to support work-life balance....
π Culture
Mithrl fosters a culture of innovation and efficiency, emphasizing the importance of leveraging AI to streamline scientific research and improve outco...

Bioinformatics Engineer β’ Lead
Mithrl β’ San Francisco
Skills & Technologies
Overview
Mithrl is seeking a Lead Bioinformatics Engineer to build and scale scientific processing pipelines. You'll work with technologies like Nextflow and handle various biological data modalities. This role requires expertise in bioinformatics and pipeline architecture.
Job Description
Who you are
You have a strong background in bioinformatics and experience in building and scaling scientific workflows β your expertise allows you to transform raw biological data into clean, reproducible outputs that drive impactful insights. You are proficient in Nextflow and have experience with various biological data modalities including microarray, imaging, spatial transcriptomics, genomics, and epigenomics. Your collaborative nature enables you to work effectively with cross-functional teams, ensuring data harmonization and schema alignment across projects. You thrive in environments where you can tackle high-impact problems and enjoy the challenge of architecting robust scientific pipelines.
Desirable
Experience with modality-specific validation and quality control layers is a plus, as is familiarity with AI-driven data analysis tools. You understand the importance of data integrity and are passionate about leveraging technology to accelerate scientific discovery. Your ability to communicate complex concepts clearly makes you a valuable team member, and you are committed to fostering an inclusive and diverse work environment.
What you'll do
In this role, you will own the workflows that power Mithrlβs AI Co-Scientist, ensuring that scientists can ask questions and receive accurate, data-backed answers instantly. You will architect and implement Nextflow and nf-core style pipelines, focusing on the transformation of messy biological data into actionable insights. Collaborating closely with the Tabular Data Team and Knowledge Curation Team, you will ensure that data harmonization, variable ID mapping, and schema alignment are maintained throughout the processing pipelines. Your work will directly contribute to the acceleration of drug discovery and the delivery of new medicines to patients.
You will also be responsible for implementing modality-specific validation and quality control layers, ensuring that the outputs of the pipelines are reliable and reproducible. As a lead engineer, you will mentor junior team members and contribute to the continuous improvement of the technical stack. Your role will involve staying updated with the latest advancements in bioinformatics and AI technologies, applying this knowledge to enhance the capabilities of Mithrlβs systems.
What we offer
Mithrl offers a dynamic work environment where innovation is at the forefront of our mission. You will be part of a team that is dedicated to transforming the landscape of drug discovery through cutting-edge technology. We provide competitive compensation and benefits, along with opportunities for professional growth and development. Join us in our mission to make scientific breakthroughs happen at the speed of thought, and help us build a future where new medicines reach patients faster than ever before.
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